Infant botulism in Australia: availability of human botulinum antitoxin for treatment.
نویسندگان
چکیده
We report the first Australian case of treatment of infant botulism with a human botulinum antitoxin developed in the United States by the California Department of Public Health. Our patient's clinical improvement was rapid, and although the product is expensive, cost-analysis supports the economical viability of its use. In future cases of suspected infant botulism, we recommend that Australian clinicians promptly obtain and administer this antitoxin to their patient.
منابع مشابه
Equine botulinum antitoxin for the treatment of infant botulism.
Infant botulism is the most common form of human botulism in Argentina and the United States. BabyBIG (botulism immune globulin intravenous [human]) is the antitoxin of choice for specific treatment of infant botulism in the United States. However, its high cost limits its use in many countries. We report here the effectiveness and safety of equine botulinum antitoxin (EqBA) as an alternative t...
متن کاملBotulism Outbreak in a Family after Ingestion of Locally Produced Cheese
Botulism is one of the most important foodborne diseases and is caused by Clostridium botulinum toxin. The main manifestations are flaccid muscle paralysis and cranial nerve palsies. Botulism is an essential health problem because of its high mortality. The diagnosis of botulism, especially in sporadic cases, is a medical challenge and a high clinical suspicion is necessary for early recognitio...
متن کاملHay fever as a Christmas gift.
The authors reply: We appreciate the additional points raised by Rao et al. and would underscore the importance of early initiation of antitoxin treatment in cases of suspected botulism. A retrospective analysis of 132 cases of foodborne botulism reported to the CDC from 1973 through 1980 showed a median hospital stay of 10 days if patients received antitoxin within 24 hours after symptoms bega...
متن کاملگزارش 4 مورد بوتولیسم غذائی در یک خانواده
Botulism is caused by a neurotoxin produced from the anaerobic, Spore-forming bacterium clostridium botulinum. Botulism have four clinical forms:1)Food –borne botulism 2)Wound botulism 3)Infant botulism 4)undetermined botulism, that the most common is food-borne botulism.  ...
متن کاملAtypical toxin variant of Clostridium botulinum type B associated with infant botulism.
An atypical toxin variant of Clostridium botulinum (strain 657) was isolated from the feces of a 6-week-old female infant whose symptoms and clinical history were consistent with infant botulism. Toxin detected in the feces and the toxin produced by isolates from the feces and from two rectal swabs could be neutralized by type B botulinal antitoxin only at very high ratios of of antitoxin to to...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Medical journal of Australia
دوره 193 10 شماره
صفحات -
تاریخ انتشار 2010